Tamoxifen Citrate Antineoplastic Crude Nolvadex

Tamoxifen Citrate Antineoplastic Crude Drug Nolvadex Tamoxifen Citrate Nolvadex Quick Details: Tamoxifen Citrate Nolvadex Usages: Tamoxifen Citrate is a potent and selective inhibitor of PKC (protein kinase C). It is known that Tamoxifen Citrate functions in PKC 蔚 translocation. Studies suggest...
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Product Details

Tamoxifen Citrate Antineoplastic Crude Drug Nolvadex

Tamoxifen Citrate Nolvadex Quick Details:

Tamoxifen Citrate

CAS 54965-24-1

Brand: SENDI

MW:563.7

MSDS: Avaiable

MF : C32H37NO8

Sample: Avaiable

Category: API

Min order: 10grams

Quality standard: In-House Standard

Place of Origin:China

 
Tamoxifen Citrate Nolvadex Usages:

Tamoxifen Citrate is a potent and selective inhibitor of PKC (protein kinase C). It is known that Tamoxifen Citrate functions in PKC 蔚 translocation. Studies suggest that Tamoxifen Citrate functions as an estrogen receptor antagonist in breast tissue. Once bound to the estrogen receptor Tamoxifen Citrate will not allow any other ligand to bind to the receptor. In contrast, Tamoxifen Citrate is an agonist towards this receptor in tissues of the endometrium. Studies indicate Tamoxifen Citrate inhibits DNA synthesis and transcription by recruiting co-repressors, which stop estrogen from interacting with genes. When combined with PAX2, Tamoxifen Citrate can inhibit the proliferation of ERBB2. It is also a high affinity activator of the GPR30 receptor. Tamoxifen Citrate is an activator of Estrogen Receptor.


Tamoxifen citrate specification

Test

Analysis Standard

Results

Characteristics

White crystalline powder

conforms

Assay

99 ~ 101.0%

99.51%

Loss on drying

≤0.5%

0.24%

Identification

IR,UV conform

conforms

Residue on ignition

≤0.2%

0.06%

Iron

≤0.005%

0.0016%

Heavy metals

≤0.001%

0.0006%

Related substances

Total:≤1.0%

0.37%

Individual:≤0.5%

0.17%

E-isomer

≤0.3%

0.20%

Organic volatile impurities

conform

conform

Conclusion

This batch is complies with  USP 39


The note of Tamoxifen Citrate Nolvadex:
1. Before using this medicine, tell your doctor about any disease, especially prostate cancer or breast cancer (male), liver, heart, kidney disease, allergies, and enlarged prostate cancer. High - dose, long - term use of male hormones, liver cancer;
2. This medicine can not be used during pregnancy. If you are pregnant or think you may be pregnant, immediately notify your doctor. Breastfeeding at the same time, should avoid using this drug;
3. Women should monitor masculine signs such as deepening of sound, beard, acne, irregular menstruation, or clitoral enlargement. If any of these occurs, consult your doctor in a timely manner;
4. Children should be very cautious, because the drug may have adverse effects on child development. Older men use this drug, there is prostate enlargement or prostate cancer risk.

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