6-Bromoandrostenedione Powder Steroids Inhibitor

CAS: 38632-00-7
MF: C19H25BrO2
MW: 365.3046
Chemical Properties Pale Yellow Solid
Usage Androstenedione (A637550) analog, an aromatase inhibitor
Usage Androstenedione analog, an aromatase inhibitor
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    Product Details

    6-Bromoandrostenedione Powder Steroids Inhibitor

    Product Name: (6b)-6-Bromoandrost-4-ene-3,17-dione
    Synonyms: 6-BRONMANDROSTENEDIONE;6-bromoandrostenedione;(6b)-6-Bromoandrost-4-ene-3,17-dione;6b-BroMoandrost-4-ene-3,17-dione;6-BroMo androstane
    CAS: 38632-00-7
    MF: C19H25BrO2
    MW: 365.3046

    Chemical Properties Pale Yellow Solid
    Usage Androstenedione (A637550) analog, an aromatase inhibitor
    Usage Androstenedione analog, an aromatase inhibitor


    6-Bromoandrostenedione Description:

    6-Bromoandrostenedione binds to aromatase,so that it can not be androgen into estrogen.Anti-aromatic enzymes such as 6-bromo-diketones are low in estrogen levels during the cycle and are also effective as PCT anti-estrogens.
    6-Bromoandrostenedione consists of two separate components:6-alpha-bromodione is a competitive inhibitor of aromatase.It prevents aromatizing androgen from acting by combining with aromatase.This is not a permanent binding force,followed by a return to normal hormone production,which later worked to normalize aromatase(and estrogen levels).


    Items

    Specifications

    Results

    Appearance

    White or almost white crystalline powder or colorless crystals

    Almost white crystalline powder

    Solubility

    Practically insoluble in water,soluble in ethanol,sparingly soluble in acetone and fatty oil

    Complies

    Identification

    IR:Complies with the reference spectrum

    Complies

    TLC:Complies

    Complies

    Specific optical rotation

    +186°to+194°(Calculated on the dry basis)

    +190°

    Related substances

    Total impurities:≤0.8%
    Impurity A:≤0.5%
    Impurity B:≤0.5%
    Impurity C:≤0.5%
    Impurity D:≤0.5%
    Impurity E:≤0.5%
    Impurity F:≤0.5%
    Impurity G:≤0.5%
    (Individual unidentified impurities):≤0.10%

    Total impurities:0.1%
    Impurity A:<0.05%
    Impurity B:<0.05%
    Impurity C:0.13%
    Impurity D:<0.05%
    Impurity E:<0.05%
    Impurity F:<0.05%
    Impurity G:<0.05%
       <0.05%

    Loss on drying

    ≤0.5%

    0.3%

    Assay(UV)

    97.0%to 103.0%(Calculated on the dry basis)

    99%

    Insoluble matter

    No substantial foreign matter is observed

    Complies

    Residual solvents

    Methylbenzene:≤890ppm
    Cyclohexanone:≤200ppm
    Ethanol:≤1000ppm

    24ppm
    27ppm
    166ppm


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