Oral Steroids Tibolone Livial Acetate Tibol Hormone
Product name: Tibolone
Liviella，Tibolone Livial， Tibolone Acetate，Tibol
Product Categories: Active Pharmaceutical Ingredients; Hormone;Acetylenes; Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone
Mol File: 5630-53-5.mol
Molecular Formula: C21H28O2
Molecular weight: 312.45
Melting Point: 169°C
Character: White powder.
Delivery: Express courier.
Usage: Pharmaceutical material
1. Tibolone Acetate Livial / Liviella is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone Acetate is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. Tibolone Acetate has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.
2. Tibolone Acetate is a synthetic hormone-type drug which is used mainly for hormone replacement therapy in post-menopausal women. It is a synthetic steroid that has the same activity as the female sex hormones estrogen and progesterone and the androgen testosterone. Tibolone Acetate helps restore hormonal balance in the body.
3. When estrogen levels are low tissues can slowly degenerate, as is experienced during menopause. In addition, low levels of estrogen can cause distressing symptoms such as hot flushes, night sweats, mood swings, reduced sex drive and vaginal dryness. Tibolone Acetate is broken down into three compounds which act in a similar way to the natural estrogen and progesterone found in the body. It restores plasma endorphin level in post-menopausal women and acts centrally to affect the thermo-regulatory system.
The postmenopausal synthesis and metabolism of estrogen and androgen are briefly reviewed with particular reference to sex steroid activity in various target organs. On the basis of this hormonal physiology, the clinical utility of Tibolone Acetate is reviewed as a therapeutic agent for the treatment of the symptomatic menopause. The effects of Tibolone Acetate on bone health and osteoporosis, cardiovascular disease, the breast, and the endometrium are summarized, and its role in clinical practice is reviewed.
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