Progesterone Mifepristone Prohormones Steroids

Progesterone Mifepristone Prohormones Steroids
Product Name: Mifepristone
CAS: 84371-65-3
MF: C29H35NO2
MW: 429.59
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Product Details

Progesterone Mifepristone Prohormones Steroids

Product Name: Mifepristone
Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;17-beta)-(11-bet;17beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-(11bet;17-beta-hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oest;-17beta-ol-3-one;4,9-dien-3-one;r38486
CAS: 84371-65-3
MF: C29H35NO2
MW: 429.59


Results Of Analysis Tests

Test

Analysis Standard

Results

Description

Light Yellowish Crystalline Powder

Light Yellowish Crystalline Powder

Identification

(1)304nm,260nm.

confirmed

Melting Point

192ºC~196ºC

192ºC~196ºC

Specific Rotation

+124°~ +129°

+127.1°

(HPLC) Related substances

(1)(Single):≤0.5%

0.31%

 

(2)(Total):≤1.0%

0.59%

Loss On Drying

≤0.5%

0.1%

Assay

≥98.5%

99.5%

Sieve analysis

≤30¦Ìm

confirmed


Mifepristone Usage
1. Abortion
Mifepristone followed by a prostaglandin analog (misoprostol or gemeprost) is used for medical abortion.
A 2011 evidence-based clinical guideline by the Royal College of Obstetricians and Gynaecologists (RCOG) says medical abortion using mifepristone followed by the prostaglandin analog misoprostol is effective and appropriate at any gestational age. A 2012 technical and policy guidance book and a 2014 clinical practice handbook by the World Health Organization (WHO) recommend mifepristone followed by the prostaglandin analog misoprostol for first and second trimester medical abortions. 2013 and 2014 practice bulletins by the American College of Obstetricians and Gynecologists (ACOG) recommend mifepristone followed by the prostaglandin analog misoprostol for first and second trimester medical abortions. Mifepristone alone results in abortion within two weeks of 54% to 92% of pregnancies.
2. Cushing's syndrome
Mifepristone is used for the medical treatment of high blood sugar (hyperglycemia) caused by high cortisol levels in the blood (hypercortisolism) in adults with endogenous Cushing’s syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or cannot have surgery.
3. Emergency contraception
Mifepristone is used for emergency contraception.


How to use mifepristone:

Read the Medication Guide provided by your doctor before you start using mifepristone. Keep the guide to reread if needed. If you have any questions, consult your doctor or pharmacist. Read and sign the Patient Agreement form provided by your doctor. Tell your doctor if you do not understand how to use this medication or cannot follow the instructions. Mifepristone is available only from your doctor. It is not available from store pharmacies.
You must visit the doctor's office at least 2 times to complete your treatment and important examinations. This treatment is only given under direct medical...


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