Oral SARMs SR9011 Steroids Powder

SR9011 Benefits:
Increase lean muscle mass
Increase strength
Increase bone density
Can be taken orally
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Product Details

Oral SARMS SR9011 Raw Powder CAS 1379686-29-9 SR-9011 with Fast Delivery

SR9011 detail:

Product name

Sr9011

CAS

1379686-29-9

Molecular Formula

C23H31ClN4O3S

Molecular Weight

471.49

Apperance

White or off-white powder

Usage

Pharmaceutical intermediates.

WhatsApp

+8618126437315

Skype

selina.xu@yccreate.com


SR9011 Application:
Synchronizing rhythms of behaviour and metabolic processes is important for cardiovascular health and preventing metabolic diseases.
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.Treatment of diet-induced obese mice with a SR9011 decreased obesity by reducing fat mass and markedly improving dyslipidaemia and hyperglycaemia.
 
SR9011 COA:

Item

Specification

Appearance

An odorless, almost white or white powder

Identificaton

The retention time of the major peak is confirm to the RS

Loss on Drying

Not more than 0.5%

Assay(HPLC)

Not less than 99.0%

Ignition residue

Not more than 0.1%

Heavy metal

Not more than 20 ppm


SR9011 Dosage:
In vitro: SR9011 was used at 5-10 µM concentration in vitro and in cellular assays.
In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.


SR9011 Benefits:
Increase lean muscle mass
Increase strength
Increase bone density
Can be taken orally


More Detail about SR9011:

SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB with an EC50 ~790 nM and REV-ERB with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB and REV-ERB play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.
The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.


Whatsapp: +8618126437315
Skype: selina.xu@yccreate.com
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We can pack according to customers' requirements.
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