Carbocaine Mepivacaine Hydrochloride CAS 1722-62-9

Product Name: Mepivacaine hydrochloride, Carbocaine
Molecular Formula: C15H23ClN2O
Molecular Weight: 282.81
EINECS: 217-023-9
CAS NO.: 1722-62-9
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Mepivacaine Hydrochloride, a tertiary amine used as a local anesthetic, is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route.

Mepivacaine hydrochloride Basic information: 

Product Name: Mepivacaine hydrochloride

Another name: carbocaine hydrochloride

Synonyms:Carbocaine monohydrochloride;Chlorocain;Meaverin;Mepicaton;Mepident;Mepivacaine monohydrochloride;Mepivastesin;Optocain;Scandicain;Scandonest;Mepivacaine HCL;2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI,8CI);Carbocaina

Molecular Formula: C15H23ClN2O
Molecular Weight: 282.81
EINECS: 217-023-9
CAS NO.: 1722-62-9

Place of Origin: Made in China (Mainland)

Type:Antibiotic and Antimicrobial Agents

Grade Standard:Medicine Grade, Phamaceutical Grade

Brand Name: SENDI

Appearance:White Powder

Assay:HPLC 99.9%

Shelf life:2 Years Proper Storage

Storage:Cool Dry Place

Molecular structure:

1722-62-9

Mepivacaine hydrochloride Usage And Synthesis:
Chemical Properties White Solid
Usage anesthetic (local)
Usage An anti-inflammatory and analgesic
Mepivacaine is a local anesthetic of the amide type. Mepivacaine has a reasonably rapid onset  and medium duration of action and is marketed under various trade names including Carbocaine and Polocaine.
Mepivacaine is used in any infiltration and regional anesthesia.
It is supplied as the hydrochloride salt of the racemate, which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties.


Mepivacaine hydrochloride Specifications:

Item

Specification

Appearance

White crystalline solid

Solubility

Soluble in water and methanol, very slightly soluble in  
chloroform, practically insoluble in ether

PH

About 4.5

Identification

A: By IR, To match with working standard

B: Melting point 149-153°

C: A solution responds to the test for Chloride

Loss on drying

≤1.0%

Residual on ignition

≤0.1%

Residue solvents

Should be matched with the standard

Chromatographic purity

≤ 0.4%

Assay

99.0%-102.0%(on the dried basis)

Mepivacaine hydrochloride Descriptions:

Mepivacaine is a local anesthetic of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine .
Mepivacaine is used in any infiltration and regional anesthesia .
It is supplied as the hydrochloride salt of the racemate, which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties.
 

Recommend Dosage of Mepivacaine hcl:

As with all local anesthetics, the dose is different, depending on the anesthetic area, the distribution of blood vessels in the tissue, the individual tolerance and anesthesia. The minimum dose required for effective anesthesia should be given. Specific technical and procedures reference standard dental manual and textbook. For upper and lower jaw permeability and obstructive injection,


The average dose of a cartridge is usually sufficient. Each cartridge contains 1.8ml (54mg 3% of the solution). Five cartridge (270mg of 3 % solution) is usually sufficient to affect the whole oral anesthesia. Whenever a wider dose is required, the maximum dose should be calculated based on the patient's weight. You can give a dose of up to 3mg per pound. In any dental clinic, the total dose for all adults should be no more than 400 mg.


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