Caspofungin Diacetate CAS 179463-17-3

Caspofungin Diacetate CAS 179463-17-3
Supply high quality Cancidas / Caspofungin Acetate cas 179463-17-3 Caspofungin Diacetate Manufacturer price Welcome to Contact Mitchell For more details Directly: Whatsapp +8618124076819 Skype: hk@chembj.com Caspofungin is the acetate salt of an antimycotic echinocandin lipopeptide,...
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Supply high quality Cancidas / Caspofungin Acetate cas 179463-17-3 Caspofungin Diacetate Manufacturer price

hk@chembj.com

Welcome to Contact Mitchell For more details Directly: Whatsapp +8618124076819 Skype:  hk@chembj.com


Caspofungin is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.


Basic details:

Product Name:Caspofungin Diacetate

CAS No.:179463-17-3

Other Names: Cancidas / Caspofungin Acetate

MF:C56H96N10O19

Place of Origin:Made in China (Mainland)

Grade Standard:Medicine Grade

Brand Name:SENDI

Purity:99%

Appearance:White Crystalline Powder

CAS:179463-17-3

Melting point:204-206 °C

boiling point:1408.1°C at 760 mmHg

flash(ing) point:805.4°C

Shelf life:2 Years

Loss on Drying:≤1,0%

Molecular structure:

179463-17-3

Caspofungin acetate is a semi-synthetic analogue of pneumocandin B0 with improved water solubility, a significant limitation in the development of the echinocandin class as pharmaceuticals. Caspofungin acts by inhibition of the synthesis of β (1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.

 

Specification OF Caspofungin Diacetate:

Item

Specifications 

   Result

Appearance

White or almost white powder

Off white powder

Indentification

 

HPLC:The retention time of principle peak obtained from 

Test solution should conform with that obtained from 

Standard solution, as test in Assay

Conforms


IR: Spectrum of Test sample should conform to that 

of Caspofungin Acetate Reference Standard

Conforms

Specific Optical Rotation

-102.0°~108.0 °

-105.3°

PH

5.0~7.0

6.5

Water

10.0%

7.5%

Solution color and clarity

Solution should be clear colorless

Conforms

Related substances I

Impurity A:  NMT 0.10%

ND


Impurity B:  NMT 0.10%

ND


Impurity D:  NMT 0.30%

0.17%


Impurity E:  NMT 0.10%

ND


Unspecified impurity F:  NMT 0.10%

0.03%


Unspecified impurity G:  NMT 0.10%

ND


Pneumocandin B0: NMT 0.10%

ND


Each of unspecified impurity : NMT 0.10%

0.04%


Total impurity:  NMT 1.0%

0.24%

Related substances II

Impurity C: NMT 0.10%

0.03%

Acetic acid

9.0%~11.0%(calculated on anhydrous basis)

10.1%

Heavy Metal as Pb

NMT 10ppm

Conforms

8

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Email: hk@chembj.com

Phone: 0086-18124076819

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