China MGF Mechano Growth 2mg/vail and 5mg/vail peptide
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What is MGF?
MGF is a variation of muscle triggered by rigorous exercise and muscle damage. Structurally different than other growth factors such as IGF-1 that is synthesized by the liver, MGF enters muscle fibers to repair skeletal muscle tissue and prevent damaged cells from dying off. It adds stem cells into the muscle and is triggered by a pulse of stimulation after muscle tissues undergo significant mechanical stress. Genes for MGF are transcribed to a lesser degree as people age, which is why muscle mass decreases in the elderly, and certain diseases also interfere with the production of it.
According to a British study say elderly men who exercised and received the growth hormone known as "mechano growth factor" (MGF) showed increased muscle mass.
MGF may also help treat age-related loss of muscle strength, which causes increased fragility
This growth hormone may also benefit patients who can't do intensive exercise because of diseases such as muscular dystrophy, amyotrophic lateral sclerosis (ALS), kidney disease or cancer. MGF may even help slow muscle loss among astronauts who spend long hours in zero gravity during space travel.
MGF, which is produced naturally when muscles are stretched during exercise, activates stem cells already present in muscle tissue. Once activated, the stem cells begin to divide and create additional muscle fibers that increase the size and strength of the muscle.
Levels of MGF decline as people age. This combined with a lack of intense physical activity, may cause muscle wasting in the elderly. While treatment with MGF may prove beneficial in such cases, the downside is that MGF has great potential for doping in sports.
Mechano growth factor (MGF) is a novel splice variant of the Insulin-Like Growth Factor-1 (IGF-1), also known as IGF-1 Ec in humans and IGF-1Eb in rodents. It is actually originally called MGF because the RNA form of it is expressed in muscle tissues in response to the overload or/and damage of muscle growth tissue. The C-terminal peptide of the mechano growth factor (MGF) is a crucial region for the alternative splicing of the peptide. The alternative splicing in the MGF is brought about by the shift in the reading frame in which a specific C-terminal sequence (E-domain) is encoded by exon 5 and the first part of the exon 6. Another interesting point in MGF is that, because of the E domain it contains, MGF can act on muscles independently from the rest of the molecule. Furthermore, MGF can elicit very different effects with mGF promoting satellite cells proliferation and IGF-1 inducing differentiation
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