TB500 2mg/vail, 5mg/vail, 10mg/vail injections Thymosin Beta 4 peptides for help injury
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CAS No.: 77591-33-4
Molecular Formula: C212H350N56O78S
Molecular Weight: 4963.49
Purity (HPLC): 99%min
Single Impurity (HPLC): 2.0%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): ≥ 80.0%
Water Content(Karl Fischer): ≤ 5.0%
Content (HPIC): ≤ 15.0%
Mass Balance: 95.0~105.0%
Appearance: White powder
TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human and animal cells. The main purpose of this peptide is to promote healing. It also promotes creation of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons, ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher concentration where tissue has been damaged. This peptide is also a very potent anti-inflamatory agent.
TB-500 has a peptide purity level that exceeds 99.9% as determined by HPLC and MS. This peptide was synthesized with no additives and is supplied as a white lyophilized (freeze-dried) powder.
TB-500 is primarily used in the treatment of various muscle injuries or pain caused by inflammation. There is very little official human data available for this product; however, it has been a long time used in racehorses. TB500, although synthetic, serves to act as a synthetic form (loosely) of Thymosin Beta4 (TB4). TB500 is not TB4; although very commonly confused as TB4, it is designed to provide the benefits of the naturally occurring thymus produced hormone.
TB-500 Functions and Traits
The thymus gland as well as in various localized cells in the human body produces thymosin Beta-4 (TB-4). TB-4 is found in cytoplasm in high levels of concentration as well as in wound fluid. TB-500 is designed to promote the actionable area - the part of TBthat promotes healing. More importantly, manufacturing TB500, despite not being TB4 is possible while the latter is extremely difficult.
HOW TO USE TB 500?
Give onesubcutaneous each week for six consecutive weeks. There after use oneper month. It's best to give 6 days before intense work.
We recommend giving the shot the day after intense work then giving the shot every seven day there after. You must make sure to hydrate very well when using this product. Give normal vitamins and minerals to support normal racing function. Hydration is key when using this product.
TB-500 is a synthetic version of the naturally occurring peptide present in virtually all human and animal cells, Thymosin Beta-4. This potent peptide is a member of a ubiquitous family of 16 related molecules with a high conservation of sequence and localization in most tissues and circulating cells in the body. TB-500 not only binds to actin, but also blocks actin polymerization and is the actin-sequestering molecule in eukaryotic cells.
TB-500 was identified as a gene that was up-regulated four-to-six fold during early blood vessel formation and found to promote the growth of new blood cells from the existing vessels. This peptide is present in wound fluid and when administered subcutaneously, it promotes wound healing, muscle building and speeds up recovery time of muscles fibres and their cells. An additional key factor of TB-500 is that it promotes cell migration through a specific interaction with actin in the cell cytoskeleton. It has been demonstrated that a central small amino acid long-actin binding domain has both blood cell reproduction and wound healing characteristics. These characteristics are uncovered by accelerating the migration of endothelial cells and keratinocytes. It also increases the production of extracellular matrix-degrading enzymes.
Studies demonstrate that TB-500 is a potent, naturally occurring wound repair factor with anti-inflammatory properties. Tß4 is different from other repair factors, such as growth factors, in that it promotes endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has a very low molecular weight meaning it can travel relatively long distances through tissues. One of TB-500 key mechanisms of action is its ability to regulate the cell-building protein, Actin, a vital component of cell structure and movement. Of the thousands of proteins present in cells, actin represents up to 10% of the total proteins which therefore plays a major role in the genetic makeup of the cell.
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